BD-PT0415

ATP-citrate synthase Rabbit Polyclonal Antibody

ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme

常规抗体

ACLY

ATP-citrate synthase

WB

Human,Mouse,Rat,Monkey

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

47

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=47

P53396

http://www.uniprot.org/uniprotkb/P53396/entry

104112

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=104112

Q91V92

http://www.uniprot.org/uniprot/Q91V92

24159

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24159

P16638

http://www.uniprot.org/uniprot/P16638

The antiserum was produced against synthesized peptide derived from human ATP-Citrate Lyase. AA range:420-469

ATP-citrate synthase Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein.

WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

120kD

-20°C/1 year

Polyclonal, Rabbit,IgG

ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],

Brain,Epithelium,Hippocampus,Liver,Lymph,Platelet,

Cytoplasm, cytosol .

Citrate cycle (TCA cycle);

catalytic activity:ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.,function:ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.,similarity:In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.,similarity:In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.,subunit:Homotetramer.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.