产品名称
AVP Receptor V3 Rabbit Polyclonal Antibody
别名
AVPR1B; AVPR3; VPR3; Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor
蛋白名称
Vasopressin V1b receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=553
Human Swissprot No.
P47901
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P47901/entry
Mouse Swissprot No.
Q9WU02
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WU02
免疫原
The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324
特异性
AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],
组织表达
Lung carcinoma,Pituitary,
细胞定位
Cell membrane ; Multi-pass membrane protein .
信号通路
Calcium;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction;
功能
function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
