产品名称
SEM4F Rabbit Polyclonal Antibody
别名
Semaphorin-4F (Semaphorin-M) (Sema M) (Semaphorin-W) (Sema W)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.336% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10505
Human Swissprot No.
O95754
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95754/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20355
Mouse Swissprot No.
Q9Z123
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z123
Rat Gene Link
https://www.uniprot.org/uniprot/29745
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z143
免疫原
Synthesized peptide derived from human SEM4F AA range: 85-135
特异性
This antibody detects endogenous levels of SEM4F at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],
组织表达
Amygdala,Brain,Liver,
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic density . Perikaryon . Cell projection, dendrite . Colocalizes with DLG4 at synapses. .
功能
function:Has growth cone collapse activity against retinal ganglion-cell axons.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
