产品名称
Arylsulfatase F Rabbit Polyclonal Antibody
别名
ARSF; Arylsulfatase F; ASF
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=416
Human Swissprot No.
P54793
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P54793/entry
免疫原
The antiserum was produced against synthesized peptide derived from human ARSF. AA range:301-350
特异性
Arylsulfatase F Polyclonal Antibody detects endogenous levels of Arylsulfatase F protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jan 2011],
功能
cofactor:Binds 1 calcium ion per subunit.,enzyme regulation:Not inhibited by DHEAS or warfarin.,PTM:The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.,similarity:Belongs to the sulfatase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
