产品名称
Arrestin-C Rabbit Polyclonal Antibody
别名
ARR3; ARRX; CAR; Arrestin-C; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=407
Human Swissprot No.
P36575
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P36575/entry
Mouse Swissprot No.
Q9EQP6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9EQP6
免疫原
The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388
特异性
Arrestin-C Polyclonal Antibody detects endogenous levels of Arrestin-C protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016],
组织表达
Inner and outer segments, and the inner plexiform regions of the retina.
细胞定位
Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment .
功能
function:May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.,similarity:Belongs to the arrestin family.,tissue specificity:Inner and outer segments, and the inner plexiform regions of the retina.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
