产品名称
ARMCX1 Rabbit Polyclonal Antibody
别名
ARMCX1; ALEX1; AD032; Armadillo repeat-containing X-linked protein 1; ARM protein lost in epithelial cancers on chromosome X 1; Protein ALEX1
蛋白名称
Armadillo repeat-containing X-linked protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51309
Human Swissprot No.
Q9P291
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9P291/entry
Mouse Swissprot No.
Q9CX83
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CX83
免疫原
The antiserum was produced against synthesized peptide derived from human ARMX1. AA range:1-50
特异性
ARMCX1 Polyclonal Antibody detects endogenous levels of ARMCX1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
armadillo repeat containing, X-linked 1(ARMCX1) Homo sapiens This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008],
组织表达
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.
细胞定位
Mitochondrion . Mitochondrion outer membrane ; Single-pass membrane protein .
功能
similarity:Contains 3 ARM repeats.,tissue specificity:Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.