产品名称
ARHGEF19 Rabbit Polyclonal Antibody
别名
ARHGEF19; Rho guanine nucleotide exchange factor 19; Ephexin-2
蛋白名称
Rho guanine nucleotide exchange factor 19
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=128272
Human Swissprot No.
Q8IW93
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IW93/entry
Mouse Swissprot No.
Q8BWA8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BWA8
免疫原
The antiserum was produced against synthesized peptide derived from human ARHGEF19. AA range:251-300
特异性
ARHGEF19 Polyclonal Antibody detects endogenous levels of ARHGEF19 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008],
组织表达
Colon,Pancreas,Tongue,
信号通路
Regulation of Actin Dynamics; AMPK
功能
function:Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH3 domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.