产品名称
LRFN1 Rabbit Polyclonal Antibody
别名
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2)
基因名称
LRFN1 KIAA1484 SALM2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.339% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/57622
Human Swissprot No.
Q9P244
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9P244/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/80749
Mouse Swissprot No.
Q2WF71
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q2WF71
Rat Gene Link
https://www.uniprot.org/uniprot/365222
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C7J6
免疫原
Synthesized peptide derived from human LRFN1 AA range: 529-579
特异性
This antibody detects endogenous levels of LRFN1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
细胞定位
Membrane ; Single-pass type I membrane protein . Cell junction, synapse . Cell junction, synapse, postsynaptic density membrane . Detected in excitatory, but not inhibitory, synaptic plasma membrane. .
功能
function:Involved in the regulation of excitatory synapses.,PTM:Glycosylated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the LRFN family.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1, DLGAP1, AMPA receptors and NMDA receptors (By similarity). Interacts with DLG4.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
