产品名称
ARHGAP9 Rabbit Polyclonal Antibody
别名
ARHGAP9; Rho GTPase-activating protein 9; Rho-type GTPase-activating protein 9
蛋白名称
Rho GTPase-activating protein 9
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64333
Human Swissprot No.
Q9BRR9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BRR9/entry
免疫原
The antiserum was produced against synthesized peptide derived from human RHG9. AA range:220-269
特异性
ARHGAP9 Polyclonal Antibody detects endogenous levels of ARHGAP9 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Predominantly expressed in peripheral blood leukocytes, spleen, and thymus.
功能
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 1 WW domain.,tissue specificity:Predominantly expressed in peripheral blood leukocytes, spleen, and thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
