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ARHGAP18 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT0317
产品名称
ARHGAP18 Rabbit Polyclonal Antibody
别名
ARHGAP18; Rho GTPase-activating protein 18; MacGAP; Rho-type GTPase-activating protein 18
类别
常规抗体
基因名称
ARHGAP18
蛋白名称
Rho GTPase-activating protein 18
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
93663
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=93663
Human Swissprot No.
Q8N392
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8N392/entry
Mouse Swissprot No.
Q8K0Q5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K0Q5
免疫原
The antiserum was produced against synthesized peptide derived from human RHG18. AA range:517-566
特异性
ARHGAP18 Polyclonal Antibody detects endogenous levels of ARHGAP18 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
预测分子量
75kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010],
组织表达
Brain,Mast cell,Melanoma,Uterus,
细胞定位
Cytoplasm .
功能
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 Rho-GAP domain.,subunit:Interacts with MPHOSPH6.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of RHG18 Antibody. The lane on the right is blocked with the RHG18 peptide.

Immunohistochemistryt analysis of paraffin-embedded human brain, using RHG18 Antibody. The lane on the right is blocked with the RHG18 peptide.

Western blot analysis of the lysates from HepG2 cells using RHG18 antibody.

Western Blot analysis of various cells using ARHGAP18 Polyclonal Antibody

Western Blot analysis of Jurkat cells using ARHGAP18 Polyclonal Antibody

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