产品名称
ARHGAP12 Rabbit Polyclonal Antibody
别名
ARHGAP12; Rho GTPase-activating protein 12; Rho-type GTPase-activating protein 12
蛋白名称
Rho GTPase-activating protein 12
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=94134
Human Swissprot No.
Q8IWW6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IWW6/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=75415
Mouse Swissprot No.
Q8C0D4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C0D4
免疫原
Synthesized peptide derived from ARHGAP12 . at AA range: 310-390
特异性
ARHGAP12 Polyclonal Antibody detects endogenous levels of ARHGAP12 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
组织表达
PCR rescued clones,Placenta,T-cell,Testis,Uterus,
功能
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 WW domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
