产品名称
ARHGAP11A Rabbit Polyclonal Antibody
别名
ARHGAP11A; KIAA0013; Rho GTPase-activating protein 11A; Rho-type GTPase-activating protein 11A
蛋白名称
Rho GTPase-activating protein 11A
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9824
Human Swissprot No.
Q6P4F7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6P4F7/entry
Mouse Swissprot No.
Q80Y19
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80Y19
免疫原
The antiserum was produced against synthesized peptide derived from human ARHGAP11A. AA range:471-520
特异性
ARHGAP11A Polyclonal Antibody detects endogenous levels of ARHGAP11A protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. [provided by RefSeq, Sep 2016],
组织表达
Bone marrow,Epithelium,Eye,Testis,Uterus,
功能
similarity:Contains 1 Rho-GAP domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
