产品名称
ARHGAP1 Rabbit Polyclonal Antibody
别名
ARHGAP1; CDC42GAP; RHOGAP1; Rho GTPase-activating protein 1; CDC42 GTPase-activating protein; GTPase-activating protein rhoOGAP; Rho-related small GTPase protein activator; Rho-type GTPase-activating protein 1; p50-RhoGAP
蛋白名称
Rho GTPase-activating protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=392
Human Swissprot No.
Q07960
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q07960/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228359
Mouse Swissprot No.
Q5FWK3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5FWK3
免疫原
The antiserum was produced against synthesized peptide derived from human RHG1. AA range:189-238
特异性
ARHGAP1 Polyclonal Antibody detects endogenous levels of ARHGAP1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. [provided by RefSeq, Aug 2012],
功能
function:GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.,similarity:Contains 1 CRAL-TRIO domain.,similarity:Contains 1 Rho-GAP domain.,subunit:Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with BNIPL.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
