产品名称
ARALAR Rabbit Polyclonal Antibody
别名
SLC25A12; ARALAR1; Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12
蛋白名称
Calcium-binding mitochondrial carrier protein Aralar1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8604
Human Swissprot No.
O75746
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O75746/entry
Mouse Swissprot No.
Q8BH59
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BH59
免疫原
The antiserum was produced against synthesized peptide derived from human CMC1. AA range:391-440
特异性
ARALAR Polyclonal Antibody detects endogenous levels of ARALAR protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012],
组织表达
Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney.
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
功能
function:Calcium-dependent mitochondrial aspartate and glutamate carrier. May have a function in the urea cycle.,miscellaneous:Binds calcium.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,similarity:Contains 4 EF-hand domains.,tissue specificity:High levels in heart and skeletal muscle, low in brain and very low in kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
.jpg)
