产品名称
S7A14 Rabbit Polyclonal Antibody
别名
Probable cationic amino acid transporter (Solute carrier family 7 member 14)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.341% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/57709
Human Swissprot No.
Q8TBB6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TBB6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/241919
Mouse Swissprot No.
Q8BXR1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BXR1
免疫原
Synthesized peptide derived from human S7A14 AA range: 50-100
特异性
This antibody detects endogenous levels of S7A14 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014],
组织表达
Expressed in skin fibroblasts.
细胞定位
Lysosome membrane ; Multi-pass membrane protein . Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.
功能
sequence caution:Translated as Glu.,similarity:Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
