产品名称
AQP11 Rabbit Polyclonal Antibody
别名
AQP11; AQPX1; PSEC0027; Aquaporin-11; AQP-11
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=282679
Human Swissprot No.
Q8NBQ7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8NBQ7/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66333
Mouse Swissprot No.
Q8BHH1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BHH1
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=286758
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q8CHM1
免疫原
Synthesized peptide derived from AQP11 . at AA range: 130-210
特异性
AQP11 Polyclonal Antibody detects endogenous levels of AQP11 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.,tissue specificity:Expressed at low levels in roots and leaves.,
组织表达
Detected in the sperm head and tail (at protein level) (PubMed:28042826). Expressed in subcutaneous adipocytes (PubMed:24845055). Expressed in testis, kidney and ejaculated spermatozoa (PubMed:19812234).
细胞定位
Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein . Cytoplasm . Cytoplasm, perinuclear region . Localizes mainly to the periphery of lipid droplets (PubMed:24845055). it accumulates partly in mitochondrial-associated endoplasmic reticulum membranes (PubMed:31546170). .
功能
domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.,tissue specificity:Expressed at low levels in roots and leaves.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
