产品名称
APOBEC3D/F Rabbit Polyclonal Antibody
别名
APOBEC3D; Probable DNA dC->dU-editing enzyme APOBEC-3D; APOBEC3F; DNA dC->dU-editing enzyme APOBEC-3F; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F
蛋白名称
Probable DNA dC->dU-editing enzyme APOBEC-3D/F
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
200316/140564
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=200316
Human Swissprot No.
Q96AK3/Q8IUX4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96AK3/entry
免疫原
The antiserum was produced against synthesized peptide derived from human APOBEC3D/F. AA range:232-281
特异性
APOBEC3D/F Polyclonal Antibody detects endogenous levels of APOBEC3D/F protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008],
组织表达
Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung.
细胞定位
Cytoplasm. Cytoplasm, P-body.
功能
cofactor:Zinc.,function:Unknown. Unable to reduce HIV-1 infectivity in vitro.,miscellaneous:It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
