产品名称
TTLL3 Rabbit Polyclonal Antibody
别名
Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (HOTTL) (Tubulin--tyrosine ligase-like protein 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.344% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/26140
Human Swissprot No.
Q9Y4R7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y4R7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/101100
Mouse Swissprot No.
A4Q9E5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A4Q9E5
免疫原
Synthesized peptide derived from human TTLL3 AA range: 357-407
特异性
This antibody detects endogenous levels of TTLL3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in brain, heart, kidney, testis, liver, lung, muscle, spleen, trachea and colon.
细胞定位
Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, flagellum axoneme .
功能
function:Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.,similarity:Belongs to the ARPC4 family.,similarity:Contains 1 TTL domain.,subunit:Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
