产品名称
Annexin III Rabbit Polyclonal Antibody
别名
ANXA3; ANX3; Annexin A3; 35-alpha calcimedin; Annexin III; Annexin-3; Inositol 1; 2-cyclic phosphate 2-phosphohydrolase; Lipocortin III; Placental anticoagulant protein III; PAP-III
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=306
Human Swissprot No.
P12429
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P12429/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11745
Mouse Swissprot No.
O35639
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35639
免疫原
The antiserum was produced against synthesized peptide derived from human Annexin III. AA range:15-64
特异性
Annexin III Polyclonal Antibody detects endogenous levels of Annexin III protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008],
组织表达
Aorta endothelial cell,Cervix,Colon carcinoma,Platelet,
细胞定位
cytoplasm,plasma membrane,membrane,axon,dendrite,phagocytic vesicle membrane,specific granule,neuronal cell body,extracellular exosome,
功能
domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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