产品名称
AMPD2 Rabbit Polyclonal Antibody
别名
AMPD2; AMP deaminase 2; AMP deaminase isoform L
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=271
Human Swissprot No.
Q01433
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q01433/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=109674
Mouse Swissprot No.
Q9DBT5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DBT5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362015
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q02356
免疫原
The antiserum was produced against synthesized peptide derived from human AMPD2. AA range:131-180
特异性
AMPD2 Polyclonal Antibody detects endogenous levels of AMPD2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
组织表达
Highly expressed in cerebellum.
功能
catalytic activity:AMP + H(2)O = IMP + NH(3).,function:AMP deaminase plays a critical role in energy metabolism.,pathway:Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.,similarity:Belongs to the adenosine and AMP deaminases family.,subunit:Homotetramer.,tissue specificity:Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
