产品名称
Ameloblastin Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=258
Human Swissprot No.
Q9NP70
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NP70/entry
Mouse Swissprot No.
O55189
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O55189
免疫原
The antiserum was produced against synthesized peptide derived from human Ameloblastin. AA range:275-324
特异性
Ameloblastin Polyclonal Antibody detects endogenous levels of Ameloblastin protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. [provided by RefSeq, Aug 2011],
组织表达
Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.
细胞定位
Secreted, extracellular space, extracellular matrix.
功能
disease:Defects in AMBN are found in patients with ameloblastomas.,function:Involved in the mineralization and structural organization of enamel.,similarity:Belongs to the ameloblastin family.,tissue specificity:Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
