产品名称
ALS2CR4 Rabbit Polyclonal Antibody
别名
TMEM237; ALS2CR4; Transmembrane protein 237; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein
蛋白名称
Transmembrane protein 237
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65062
Human Swissprot No.
Q96Q45
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96Q45/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=381259
Mouse Swissprot No.
Q3V0J1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3V0J1
免疫原
The antiserum was produced against synthesized peptide derived from human ALS2CR4. AA range:181-230
特异性
ALS2CR4 Polyclonal Antibody detects endogenous levels of ALS2CR4 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a tetraspanin protein that is thought to be involved in WNT signaling. Defects in this gene are a cause of Joubert syndrome-14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
组织表达
Brain,Fetal skin,Ovary,
细胞定位
Membrane ; Multi-pass membrane protein . Cell projection, cilium . Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L.
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
