产品名称
ALDH3B1 Rabbit Polyclonal Antibody
别名
ALDH3B1; ALDH7; Aldehyde dehydrogenase family 3 member B1; Aldehyde dehydrogenase 7
蛋白名称
Aldehyde dehydrogenase family 3 member B1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=221
Human Swissprot No.
P43353
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P43353/entry
Mouse Swissprot No.
Q80VQ0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80VQ0
免疫原
The antiserum was produced against synthesized peptide derived from human ALDH3B1. AA range:51-100
特异性
ALDH3B1 Polyclonal Antibody detects endogenous levels of ALDH3B1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
组织表达
Highest expression in kidney and lung.
细胞定位
Cell membrane ; Lipid-anchor . Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.
信号通路
Glycolysis / Gluconeogenesis;Histidine metabolism;Tyrosine metabolism;Phenylalanine metabolism;Metabolism of xenobiotics by cytochrome P450;Drug metabolism;
功能
catalytic activity:An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,tissue specificity:Highest expression in kidney and lung.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
