产品名称
ALDH1B1 Rabbit Polyclonal Antibody
别名
ALDH1B1; ALDH5; ALDHX; Aldehyde dehydrogenase X; mitochondrial; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1
蛋白名称
Aldehyde dehydrogenase X mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=219
Human Swissprot No.
P30837
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30837/entry
Mouse Swissprot No.
Q9CZS1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CZS1
免疫原
The antiserum was produced against synthesized peptide derived from human ALDH1B1. AA range:311-360
特异性
ALDH1B1 Polyclonal Antibody detects endogenous levels of ALDH1B1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008],
组织表达
Liver, testis and to a lesser extent in brain.
细胞定位
Mitochondrion matrix.
信号通路
Glycolysis / Gluconeogenesis;Ascorbate and aldarate metabolism;Fatty acid metabolism;Valine; leucine and isoleucine degradation;Lysine degradation;Arginine and proline metabolism;Histidine metabolism;Tryptophan metabolism;beta-Alanine metabolism;Glyceroli
功能
catalytic activity:An aldehyde + NAD(+) + H(2)O = an acid + NADH.,function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.,pathway:Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer.,tissue specificity:Liver, testis and to a lesser extent in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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