产品名称
AKR1CL2 Rabbit Polyclonal Antibody
别名
AKR1E2; AKR1CL2; AKRDC1; 1; 5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis-specific protein; hTSP
蛋白名称
1,5-anhydro-D-fructose reductase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83592
Human Swissprot No.
Q96JD6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96JD6/entry
Mouse Swissprot No.
Q9DCT1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DCT1
免疫原
The antiserum was produced against synthesized peptide derived from human AKR1CL2. AA range:141-190
特异性
AKR1CL2 Polyclonal Antibody detects endogenous levels of AKR1CL2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
组织表达
Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078).
功能
catalytic activity:1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.,function:Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Testis-specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
