产品名称
AKR1A1 Rabbit Polyclonal Antibody
别名
AKR1A1; ALDR1; ALR; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1
蛋白名称
Alcohol dehydrogenase [NADP(+)]
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10327
Human Swissprot No.
P14550
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P14550/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58810
Mouse Swissprot No.
Q9JII6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JII6
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=78959
Rat Swissprot Link
http://www.uniprot.org/uniprot/P51635
免疫原
Synthesized peptide derived from AKR1A1 . at AA range: 250-330
特异性
AKR1A1 Polyclonal Antibody detects endogenous levels of AKR1A1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011],
组织表达
Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
细胞定位
Cytoplasm, cytosol . Apical cell membrane .
信号通路
Glycolysis / Gluconeogenesis;Glycerolipid metabolism;
功能
catalytic activity:An alcohol + NADP(+) = an aldehyde + NADPH.,function:Catalyzes the NADPH-dependent reduction of a variety of aldehydes to their corresponding alcohols.,similarity:Belongs to the aldo/keto reductase family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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