产品名称
AIFL Rabbit Polyclonal Antibody
别名
AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein
蛋白名称
Apoptosis-inducing factor 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=150209
Human Swissprot No.
Q96NN9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96NN9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72168
Mouse Swissprot No.
Q3TY86
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3TY86
免疫原
The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59
特异性
AIFL Polyclonal Antibody detects endogenous levels of AIFL protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,
组织表达
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
细胞定位
Mitochondrion . Does not translocate to the nucleus upon induction of apoptosis.
功能
domain:The Rieske domain induces apoptosis.,function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.,similarity:Belongs to the FAD-dependent oxidoreductase family.,similarity:Contains 1 Rieske domain.,subcellular location:Does not translocate to the nucleus upon induction of apoptosis.,tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
