产品名称
ADP-GK Rabbit Polyclonal Antibody
别名
ADPGK; PSEC0260; ADP-dependent glucokinase; ADP-GK; ADPGK; RbBP-35
蛋白名称
ADP-dependent glucokinase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83440
Human Swissprot No.
Q9BRR6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BRR6/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72141
Mouse Swissprot No.
Q8VDL4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VDL4
免疫原
The antiserum was produced against synthesized peptide derived from human ADPGK. AA range:241-290
特异性
ADP-GK Polyclonal Antibody detects endogenous levels of ADP-GK protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008],
组织表达
Brain,Heart,Kidney,Lymph node,Teratocarcinoma,Testis,
功能
catalytic activity:ADP + D-glucose = AMP + D-glucose 6-phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency.,pathway:Carbohydrate degradation; glycolysis.,similarity:Belongs to the ADP-dependent glucokinase family.,similarity:Contains 1 ADPK (ADP-dependent kinase) domain.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
