产品名称
Adenosine A1-R Rabbit Polyclonal Antibody
别名
ADORA1; Adenosine receptor A1
蛋白名称
Adenosine receptor A1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=134
Human Swissprot No.
P30542
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30542/entry
Mouse Swissprot No.
Q60612
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60612
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29290
Rat Swissprot Link
http://www.uniprot.org/uniprot/P25099
免疫原
The antiserum was produced against synthesized peptide derived from human ADORA1. AA range:277-326
特异性
Adenosine A1-R Polyclonal Antibody detects endogenous levels of Adenosine A1-R protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Brain,Heart,Hippocampus,
细胞定位
Cell membrane ; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.