产品名称
ADAM32 Rabbit Polyclonal Antibody
别名
ADAM32; Disintegrin and metalloproteinase domain-containing protein 32; ADAM 32
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 32
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=203102
Human Swissprot No.
Q8TC27
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8TC27/entry
Mouse Swissprot No.
Q8K410
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K410
免疫原
Synthesized peptide derived from ADAM32 . at AA range: 460-540
特异性
ADAM32 Polyclonal Antibody detects endogenous levels of ADAM32 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
ADAM metallopeptidase domain 32(ADAM32) Homo sapiens This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],
细胞定位
Membrane ; Single-pass type I membrane protein .
功能
function:May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,tissue specificity:Testis specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
