BD-PT0098

Actin α3 Rabbit Polyclonal Antibody

ACTG2; ACTA3; ACTL3; ACTSG; Actin; gamma-enteric smooth muscle; Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin

常规抗体

ACTG2

Actin gamma-enteric smooth muscle

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

72

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72

P63267

http://www.uniprot.org/uniprotkb/P63267/entry

11468

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11468

P63268

http://www.uniprot.org/uniprot/P63268

25365

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25365

P63269

http://www.uniprot.org/uniprot/P63269

The antiserum was produced against synthesized peptide derived from human Actin-gamma2. AA range:1-50

Actin α3 Polyclonal Antibody detects endogenous levels of Actin α3 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

45kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010],

In the intestine, abundantly expressed in smooth muscle cells of muscularis mucosa and muscularis propria. Also detected in intestinal vascular smooth muscle cells.

Cytoplasm, cytoskeleton.

Vascular smooth muscle contraction;

function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the actin family.,subunit:Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.