产品名称
CNNM4 Rabbit Polyclonal Antibody
别名
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)
基因名称
CNNM4 ACDP4 KIAA1592
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.358% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/26504
Human Swissprot No.
Q6P4Q7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P4Q7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/94220
Mouse Swissprot No.
Q69ZF7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q69ZF7
Rat Gene Link
https://www.uniprot.org/uniprot/363216
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C588
免疫原
Synthesized peptide derived from human CNNM4 AA range: 18-68
特异性
This antibody detects endogenous levels of CNNM4 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq, Feb 2010],
组织表达
Widely expressed. Highly expressed in heart.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions.,miscellaneous:Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo.,similarity:Belongs to the ACDP family.,similarity:Contains 2 CBS domains.,subunit:Interacts with COX11.,tissue specificity:Widely expressed. Highly expressed in heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
