产品名称
ABHD7 Rabbit Polyclonal Antibody
别名
EPHX4; ABHD7; EPHXRP; Epoxide hydrolase 4; Abhydrolase domain-containing protein 7; Epoxide hydrolase-related protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=253152
Human Swissprot No.
Q8IUS5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IUS5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=384214
Mouse Swissprot No.
Q6IE26
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6IE26
免疫原
The antiserum was produced against synthesized peptide derived from human ABHD7. AA range:101-150
特异性
ABHD7 Polyclonal Antibody detects endogenous levels of ABHD7 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight-stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD7 is a 362 amino acid single-pass type II membrane protein that belongs to the AB hydrolase superfamily and the Epoxide hydrolase family.
细胞定位
Membrane ; Single-pass type II membrane protein .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
