产品名称
ABCF1 Rabbit Polyclonal Antibody
别名
ABCF1; ABC50; ATP-binding cassette sub-family F member 1; ATP-binding cassette 50; TNF-alpha-stimulated ABC protein
蛋白名称
ATP-binding cassette sub-family F member 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23
Human Swissprot No.
Q8NE71
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8NE71/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=224742
Mouse Swissprot No.
Q6P542
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6P542
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=85493
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q6MG08
免疫原
Synthesized peptide derived from ABCF1 . at AA range: 760-840
特异性
ABCF1 Polyclonal Antibody detects endogenous levels of ABCF1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform 2]: Cytoplasm . Nucleus, nucleoplasm . Nucleus envelope .
功能
function:May function in mRNA translation.,induction:By TNF (in cultured synoviocytes).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. EF3 subfamily.,similarity:Contains 2 ABC transporter domains.,subunit:Interacts with eukaryotic initiation factor 2 (eIF2). Associates with the ribosomes.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
