BD-PT0050

ABCD4 Rabbit Polyclonal Antibody

ABCD4; PXMP1L; ATP-binding cassette sub-family D member 4; PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69

常规抗体

ABCD4

ATP-binding cassette sub-family D member 4

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

5826

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5826

O14678

http://www.uniprot.org/uniprotkb/O14678/entry

19300

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19300

O89016

http://www.uniprot.org/uniprot/O89016

The antiserum was produced against synthesized peptide derived from human ABCD4. AA range:111-160

ABCD4 Polyclonal Antibody detects endogenous levels of ABCD4 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

70kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxi

Ubiquitous.

Endoplasmic reticulum membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Targeted by LMBRD1 lysosomal chaperone to the lysosomal membrane. .

ABC transporters;

similarity:Belongs to the ABC transporter family. ALD subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 ABC transporter domain.,subunit:Homodimer or heterodimer .,tissue specificity:Ubiquitous.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.