产品名称
ASIC5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51802
Human Swissprot No.
Q9NY37
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NY37/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/58170
Mouse Swissprot No.
Q9R0Y1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R0Y1
Rat Gene Link
https://www.uniprot.org/uniprot/63866
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R0W5
免疫原
Synthesized peptide derived from human ASIC5 AA range: 412-462
特异性
This antibody detects endogenous levels of ASIC5 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. [provided by RefSeq, Jul 2008],
组织表达
Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.,similarity:Belongs to the amiloride-sensitive sodium channel family.,subunit:Homotetramer or heterotetramer.,tissue specificity:Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
