产品名称
VATO Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/533
Human Swissprot No.
Q99437
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99437/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/114143
Mouse Swissprot No.
Q91V37
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91V37
免疫原
Synthesized peptide derived from human VATO AA range: 149-199
特异性
This antibody detects endogenous levels of VATO at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
细胞定位
Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Multi-pass membrane protein .
功能
function:Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.,similarity:Belongs to the V-ATPase proteolipid subunit family.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
