产品名称
OZF Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/7705
Human Swissprot No.
Q15072
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15072/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/26465
Mouse Swissprot No.
Q8BQN6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BQN6
免疫原
Synthesized peptide derived from human OZF AA range: 3-53
特异性
This antibody detects endogenous levels of OZF at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers.
功能
miscellaneous:Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.,PTM:Sumoylated.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 10 C2H2-type zinc fingers.,subunit:Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP.,tissue specificity:Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
