产品名称
MLEC Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9761
Human Swissprot No.
Q14165
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14165/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/109154
Mouse Swissprot No.
Q6ZQI3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZQI3
Rat Gene Link
https://www.uniprot.org/uniprot/304543
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5FVQ4
免疫原
Synthesized peptide derived from human MLEC AA range: 165-215
特异性
This antibody detects endogenous levels of MLEC at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type I membrane protein .
功能
function:Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation.,similarity:Belongs to the malectin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
