产品名称
MTCH2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23788
Human Swissprot No.
Q9Y6C9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y6C9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/56428
Mouse Swissprot No.
Q791V5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q791V5
免疫原
Synthesized peptide derived from human MTCH2 AA range: 59-109
特异性
This antibody detects endogenous levels of MTCH2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015],
细胞定位
Mitochondrion outer membrane ; Multi-pass membrane protein .
功能
function:The substrate transported is not yet known. Induces mitochondrial depolarization.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 2 Solcar repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
