产品名称
FOXG1 Rabbit Polyclonal Antibody
基因名称
FOXG1 FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FOXG1A FOXG1B FOXG1C
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2290
Human Swissprot No.
P55316
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P55316/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/15228
Mouse Swissprot No.
Q60987
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q60987
Rat Gene Link
https://www.uniprot.org/uniprot/24370
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q00939
免疫原
Synthesized peptide derived from human FOXG1 AA range: 247-297
特异性
This antibody detects endogenous levels of FOXG1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012],
组织表达
Expression is restricted to the neurons of the developing telencephalon.
功能
caution:PubMed:7959731 claims that there are 3 different FOXG1 proteins, FOXG1A, FOXG1B, and FOXG1C. It was latter found that there is only one gene and the differences between these three may be sequencing errors since the protein is coded in a unique exon.,function:Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Interacts with KDM5B.,tissue specificity:Expression is restricted to the neurons of the developing telencephalon.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
