BD-PP0762

Rho GDIα (phospho Ser174) Rabbit Polyclonal Antibody

ARHGDIA; GDIA1; Rho GDP-dissociation inhibitor 1; Rho GDI 1; Rho-GDI alpha

常规抗体

ARHGDIA

Rho GDP-dissociation inhibitor 1

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

396

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=396

P52565

http://www.uniprot.org/uniprotkb/P52565/entry

192662

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=192662

Q99PT1

http://www.uniprot.org/uniprot/Q99PT1

360678

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=360678

Q5XI73

http://www.uniprot.org/uniprot/Q5XI73

The antiserum was produced against synthesized peptide derived from human ARHGDIA around the phosphorylation site of Ser174. AA range:140-189

Phospho-Rho GDIα (S174) Polyclonal Antibody detects endogenous levels of Rho GDIα protein only when phosphorylated at S174.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

23kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Brain,Cajal-Retzius cell,Colon,Epithelium,Fetal brain cortex,Lung,M

Cytoplasm .

Neurotrophin;

function:Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.,similarity:Belongs to the Rho GDI family.,subunit:Monomer.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.