BD-PP0677-TH (phospho Ser8) Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

TH (phospho Ser8) Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PP0677

产品名称

TH (phospho Ser8) Rabbit Polyclonal Antibody

别名

TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH

类别

常规抗体

基因名称

蛋白名称

Tyrosine 3-monooxygenase

推荐应用

反应种属

Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Rat Gene ID

25085

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25085

Rat Swissprot No.

P04177

Rat Swissprot Link

http://www.uniprot.org/uniprot/P04177

免疫原

The antiserum was produced against synthesized peptide derived from mouse Tyrosine Hydroxylase around the phosphorylation site of Ser8. AA range:2-51

特异性

Phospho-TH (S8) Polyclonal Antibody detects endogenous levels of TH protein only when phosphorylated at S8.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

预测分子量

62kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human brain, using Tyrosine Hydroxylase （Phospho-Ser8） Antibody. The picture on the right is blocked with the phospho peptide.

Western blot analysis of lysates from HepG2 cells treated with Anisomycin 25ug/ml 30‘, using Tyrosine Hydroxylase （Phospho-Ser8） Antibody. The lane on the right is blocked with the phospho peptide.

Western blot analysis of 293T 3T3 lysis using Phospho-TH （S8） antibody. Antibody was diluted at 1:1000