产品名称
Thymidine Kinase (phospho Ser13) Rabbit Polyclonal Antibody
别名
TK1; Thymidine kinase; cytosolic
蛋白名称
Thymidine kinase cytosolic
反应种属
Human,Mouse,Rat,Pig(Test by out customer)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7083
Human Swissprot No.
P04183
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P04183/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21877
Mouse Swissprot No.
P04184
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P04184
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24834
Rat Swissprot Link
http://www.uniprot.org/uniprot/P27158
免疫原
The antiserum was produced against synthesized peptide derived from human TK around the phosphorylation site of Ser13. AA range:1-50
特异性
Phospho-Thymidine Kinase (S13) Polyclonal Antibody detects endogenous levels of Thymidine Kinase protein only when phosphorylated at S13.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate.,miscellaneous:Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.,PTM:Phosphorylated on Ser-13 in mitosis.,similarity:Belongs to the thymidine kinase family.,
组织表达
Epithelium,Lymph,Skin,Uterus,
信号通路
Pyrimidine metabolism;Drug metabolism;
功能
catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate.,miscellaneous:Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.,PTM:Phosphorylated on Ser-13 in mitosis.,similarity:Belongs to the thymidine kinase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
