BD-PP0626-DOR-1 (phospho Ser363) Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

DOR-1 (phospho Ser363) Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PP0626

产品名称

DOR-1 (phospho Ser363) Rabbit Polyclonal Antibody

别名

OPRD1; OPRD; Delta-type opioid receptor; D-OR-1; DOR-1

类别

常规抗体

基因名称

OPRD1

蛋白名称

Delta-type opioid receptor

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

4985

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4985

Human Swissprot No.

P41143

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P41143/entry

Mouse Gene ID

18386

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18386

Mouse Swissprot No.

P32300

Mouse Swissprot Link

http://www.uniprot.org/uniprot/P32300

Rat Gene ID

24613

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24613

Rat Swissprot No.

P33533

Rat Swissprot Link

http://www.uniprot.org/uniprot/P33533

免疫原

The antiserum was produced against synthesized peptide derived from human Opioid Receptor-delta around the phosphorylation site of Ser363. AA range:323-372

特异性

Phospho-DOR-1 (S363) Polyclonal Antibody detects endogenous levels of DOR-1 protein only when phosphorylated at S363.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

预测分子量

36kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

function:Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins.,online information:Delta opioid receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with GPRASP1.,

组织表达

Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.

细胞定位

Cell membrane ; Multi-pass membrane protein .

信号通路

Neuroactive ligand-receptor interaction;

功能

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Enzyme-Linked Immunosorbent Assay （Phospho-ELISA） for Immunogen Phosphopeptide （Phospho-left） and Non-Phosphopeptide （Phospho-right）, using Opioid Receptor-delta （Phospho-Ser363） Antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using Opioid Receptor-delta （Phospho-Ser363） Antibody. The picture on the right is blocked with the phospho peptide.

Western blot analysis of lysates from 293 cells treated with TSA 400nM 24h, using Opioid Receptor-delta （Phospho-Ser363） Antibody. The lane on the right is blocked with the phospho peptide.

Western Blot analysis of 293 cells using Phospho-DOR-1 （S363） Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.