产品名称
FOXP4 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/116113
Human Swissprot No.
Q8IVH2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IVH2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74123
Mouse Swissprot No.
Q9DBY0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DBY0
免疫原
Synthesized peptide derived from human FOXP4 AA range: 307-357
特异性
This antibody detects endogenous levels of FOXP4 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Jul 2008],
功能
domain:The leucine-zipper is required for dimerization and transcriptional repression.,function:Transcriptional repressor that represses lung-specific expression.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Forms homodimers and heterodimers with FOXP1 and FOXP2. Dimerization is required for DNA-binding.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
