产品名称
GLTL4 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/374378
Human Swissprot No.
Q6P9A2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P9A2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/233733
Mouse Swissprot No.
Q8K1B9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K1B9
免疫原
Synthesized peptide derived from human GLTL4 AA range: 144-194
特异性
This antibody detects endogenous levels of GLTL4 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
catalytic activity:UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide.,cofactor:Calcium.,cofactor:Manganese.,domain:The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.,domain:There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.,function:May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.,similarity:Contains 1 ricin B-type lectin domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
