产品名称
WASH1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/100287171
Human Swissprot No.
A8K0Z3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/A8K0Z3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/68767
Mouse Swissprot No.
Q8VDD8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VDD8
Rat Gene Link
https://www.uniprot.org/uniprot/367328
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B2RYF7
免疫原
Synthesized peptide derived from human WASH1 AA range: 163-213
特异性
This antibody detects endogenous levels of WASH1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
细胞定位
Early endosome membrane . Recycling endosome membrane . Late endosome . Cytoplasmic vesicle, autophagosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localization to the endosome membrane is mediated via its interaction with WASHC2 (PubMed:19922874). Localizes to MMP14-positive late endosomes and transiently to invadipodia (PubMed:24344185). Localized to Salmonella typhimurium entry sites (By similarity). .
功能
miscellaneous:The telomeric region of chromosome 9p is paralogous to the pericentromeric regions of chromosome 9 as well as to 2q. Paralogous regions contain 7 transcriptional units, including CXYorf1. Duplicated CXYorf1 genes are also present in the Xq/Yq pseudoautosomal region, as well as on chromosome 1 and 15. The chromosome 16 copy seems to be a pseudogene.,similarity:Belongs to the FAM39 family.,similarity:Contains 1 WH2 domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.