产品名称
TMTC2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/160335
Human Swissprot No.
Q8N394
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N394/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/278279
Mouse Swissprot No.
Q56A06
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q56A06
免疫原
Synthesized peptide derived from human TMTC2 AA range: 184-234
特异性
This antibody detects endogenous levels of TMTC2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016],
细胞定位
Membrane ; Multi-pass membrane protein . Endoplasmic reticulum .
功能
similarity:Belongs to the TMTC family.,similarity:Contains 10 TPR repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.