产品名称
CL16A Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23274
Human Swissprot No.
Q2KHT3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q2KHT3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74374
Mouse Swissprot No.
Q80U30
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80U30
免疫原
Synthesized peptide derived from human CL16A AA range: 129-179
特异性
This antibody detects endogenous levels of CL16A at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
组织表达
Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells.
细胞定位
Endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Associates with the endolysosome membrane. .
功能
disease:Defects in CLEC16A might be a cause of insulin-dependent diabetes mellitus (IDDM) [MIM:222100].,similarity:Belongs to the CLEC16A/gop-1 family.,tissue specificity:Almost exclusively expressed in immune cells, including dendritic cells, B lymphocytes and natural killer cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
